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Coil-globule Transition: Biomedical engineering, Cross-link, Polymer, Poly(N-isopropylacrylamide), Upper critical solution temperature, Lower critical
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| Please note that the content of this book primarily consists of articles
available from Wikipedia or other free sources online. In polymer
physics, the Coil-globule transition is the collapse of a macromolecule
from an expanded coil state through an ideal coil state to a collapsed
globule state, or vice-versa. The coil-globule transition is of
importance in biology due to the presence of coil-globule transitions in
biological macromolecules such as proteins and DNA. It is also analogous
with the swelling behavior of a crosslinked polymer gel and is thus of
interest in biomedical engineering for controlled drug delivery. A
particularly prominent example of a polymer possessing a coil-globule
transition of interest in this area is that of Poly. |
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