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CDC6: Protein, Genetic Code, Macromolecule, Polysaccharide, Nucleic Acid, Enzyme, Catalysis
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Dieser Artikel gilt, aufgrund seiner Grösse, beim Versand als 2 Artikel!
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| Please note that the content of this book primarily consists of articles
available from Wikipedia or other free sources online. Cell division
control protein 6 homolog is a protein that in humans is encoded by the
CDC6 gene.The protein encoded by this gene is highly similar to
Saccharomyces cerevisiae Cdc6, a protein essential for the initiation of
DNA replication. This protein functions as a regulator at the early
steps of DNA replication. It localizes in cell nucleus during cell cycle
G1, but translocates to the cytoplasm at the start of S phase. The
subcellular translocation of this protein during cell cycle is regulated
through its phosphorylation by Cyclin-dependent kinases. Transcription
of this protein was reported to be regulated in response to mitogenic
signals through transcriptional control mechanism involving E2F
proteins. |
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