This book approaches biomaterials science not just from materials science and engineering perspectives, but also from the clinical side. It engages biomaterials engineers and physicians in a much-needed discussion that integrates both fields at many levels, helping them increase the rate of successful deployment of biomaterials, lower the side effects of such a deployment, and accumulate knowledge for improving current methodologies and meeting future challenges. Leading contributors address topics such as hemocompatibility, carcinogenesis, infections, and cellular mechanisms, as well as signal transduction, clinical trials, MEMS, nanotechnology, FDA regulations, and ethical issues.