The first chapter by Martin Burger provides an overview of recent developments related to Bregman distances, which is an important tool in inverse problems and image processing. The chapter by Piotr Kalita studies the operator version of a firstorder in time partial differential inclusion and its time discretization. In the chapter by Günter Leugering, Jan Soko?owski and Antoni ?ochowski, nonsmooth shape optimization problems for variational inequalities are considered. The next chapter, by Katja Mombaur is devoted to applications of optimal control and inverse optimal control in the field of medical and rehabilitation technology, in particular in human movement analysis, therapy and improvement by means of medical devices. The final chapter, by Nikolai Osmolovskii and Helmut Maurer provides a survey on no-gap second order optimality conditions in the calculus of variations and optimal control, and a discussion of their further development.