This book constitutes the refereed proceedings of the 11th Asia-Pacific Computer Systems Architecture Conference, ACSAC 2006. The book presents 60 revised full papers together with 3 invited lectures, addressing such issues as processor and network design, reconfigurable computing and operating systems, and low-level design issues in both hardware and systems. Coverage includes large and significant computer-based infrastructure projects, the challenges of stricter budgets in power dissipation, and more.